Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL1889283 | 0.97 | TSHR (0.48) | SPHK1TSHRTHRBLMNACYP2D6 | |
| Heptane SCHEMBL7200232 | 0.89 | SPHK1 (0.42) | SPHK1TSHRMAPTGPR84FFAR1 | |
| Heptane SCHEMBL1399518 | 0.88 | TSHR (0.57) | SPHK1TSHRTHRBLMNAALDH1A1 | |
| Hexane SCHEMBL7047481 | 0.85 | GPR84 (0.43) | TSHRALDH1A1HSD17B10MEN1KMT2A | |
| Decane SCHEMBL11321882 | 0.85 | TSHR (0.61) | SPHK1TSHRTHRBLMNAALDH1A1 | |
| Heptane SCHEMBL6217 | 0.85 | TSHR (0.61) | SPHK1TSHRTHRBLMNAALDH1A1 | |
| Nonane SCHEMBL3803426 | 0.85 | TSHR (0.61) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| Heptane SCHEMBL11839960 | 0.85 | TSHR (0.61) | TSHRTHRBLMNAALDH1A1HSD17B10 | |
| Heptane SCHEMBL9263200 | 0.85 | TSHR (0.61) | SPHK1TSHRTHRBLMNAALDH1A1 | |
| Heptane SCHEMBL730699 | 0.85 | TSHR (0.61) | TSHRTHRBLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116854-B1 | NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA ZRT (HU) | 2022-01-26 | — | — | EP | disclosed |
| US-10000601-B2 | Metathesized triacylglycerol polyols for use in polyurethane applications and their related properties | TRENT UNIVERSITY (CA) | 2018-06-19 | — | — | US | disclosed |
| US-10000724-B2 | Metathesized triacylglycerol green polyols from palm oil for use in polyurethane applications and their related properties | TRENT UNIVERSITY (CA) | 2018-06-19 | — | — | US | disclosed |
| US-9777245-B2 | Methods of fractionating metathesized triacylglycerol polyols and uses thereof | TRENT UNIVERSITY (CA) | 2017-10-03 | — | — | US | disclosed |
| US-20170037002-A1 | NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2017-02-09 | — | — | US | disclosed |
| EP-3116854-A1 | NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS | CHINOIN GYÓGYSZER ES VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 2017-01-18 | — | — | EP | disclosed |
| US-20160312151-A1 | Methods of Fractionating Metathesized Triacylglycerol Polyols and Uses Thereof | TRENT UNIVERSITY (CA) | 2016-10-27 | — | — | US | disclosed |
| US-20150337073-A1 | METATHESIZED TRIACYLGLYCEROL POLYOLS FOR USE IN POLYURETHANE APPLICATIONS AND THEIR RELATED PROPERTIES | TRENT UNIVERSITY (CA) | 2015-11-26 | — | — | US | disclosed |
| WO-2015136317-A1 | NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2015-09-17 | — | — | WO | disclosed |
| EP-2208724-B1 | Process for purification of latanoprost, synthetic analogue of prostaglandin PGF 2alfa | IND CHIMICA SRL (IT) | 2011-12-07 | — | — | EP | disclosed |
| EP-2208724-A1 | Process for purification of latanoprost, synthetic analogue of prostaglandin PGF 2alfa | INDUSTRIALE CHIMICA S.r.l. (IT) | 2010-07-21 | — | — | EP | disclosed |
| US-7709478-B2 | Acylated 6,7,8,9-tetrahydro-5H-benzocycloheptenyl amines and their use as pharmaceutical agents | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-05-04 | — | — | US | disclosed |
| US-7498458-B2 | Process for the preparation of prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED (GB) | 2009-03-03 | — | — | US | disclosed |
| US-7268239-B2 | Process for the preparation of prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED (GB) | 2007-09-11 | — | — | US | disclosed |
| US-20050272877-A1 | Process for the preparation of prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED (GB) | 2005-12-08 | — | — | US | disclosed |
| US-20050261374-A1 | Process for the preparation of prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED | 2005-11-24 | — | — | US | disclosed |
| US-20040249172-A1 | Process for the preparationof prostaglandins and analogues thereof | RESOLUTION CHEMICALS LIMITED (GB) | 2004-12-09 | — | — | US | disclosed |
| US-6759412-B2 | FOR PRODUCING DRUGS USED FOR THERAPY OF CARDIOVASCULAR DISEASES, STABLE OR UNSTABLE ANGINA PECTORIS, CORONARY HEART DISEASE, PRINZMETAL ANGINA, ACUTE CORONARY SYNDROME, HEART FAILURE, MYOCARDIAL INFARCTION, STROKE, THROMBOSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-06 | — | — | US | disclosed |
| EP-1362027-A2 | ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYL AMINES AND THEIR USE AS PHARMACEUTICAL | Aventis Pharma Deutschland GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002064546-A2 | ACYLATED 6,7,8,9-TETRAHYDRO-5H-BENZOCYCLOHEPTENYL AMINES AND THEIR USE AS PHARMACEUTICAL | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037002-A1 | NEW PROCESS FOR THE PREPARATION OF HIGH PURITY PROSTAGLANDINS | PTGES3, PTGER3, PTGES | SPHK1 1009/4885TSHR 2693/4885THRB 4226/4885 |
| US-20150337073-A1 | METATHESIZED TRIACYLGLYCEROL POLYOLS FOR USE IN POLYURETHANE APPLICATIONS AND THEIR RELATED PROPERTIES | MGLL, PNLIP, DAGLA | SPHK1 329/4885TSHR 4576/4885THRB 3279/4885 |
| US-20040249172-A1 | Process for the preparationof prostaglandins and analogues thereof | PTGIS, PTGES, PTGES2 | SPHK1 680/4885TSHR 3394/4885THRB 4144/4885 |
| US-20050261374-A1 | Process for the preparation of prostaglandins and analogues thereof | PTGIS, PTGES, PTGES2 | SPHK1 614/4885TSHR 3002/4885THRB 3550/4885 |
| US-10000601-B2 | Metathesized triacylglycerol polyols for use in polyurethane applications and their related properties | MGLL, PNLIP, DAGLA | SPHK1 329/4885TSHR 4576/4885THRB 3279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.