Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714949 | 0.88 | ALOX15 (0.49) | KMT2AALOX15SMN1; SMN2CISD1MEN1 | |
| SCHEMBL31146819 | 0.86 | ABL1 (0.51) | KMT2AALOX15SMN1; SMN2CISD1MEN1 | |
| SCHEMBL31146773 | 0.86 | ABL1 (0.51) | KMT2AALOX15SMN1; SMN2CISD1MEN1 | |
| SCHEMBL12471164 | 0.85 | KMT2A (0.43) | KMT2AALOX15LMNASMN1; SMN2KDM4E | |
| SCHEMBL18208607 | 0.81 | KMT2A (0.44) | KMT2AALOX15KDM4ENPSR1POLB | |
| SCHEMBL1521870 | 0.81 | PKM (0.45) | KMT2ALMNAKDM4EIDO1POLB | |
| SCHEMBL7531364 | 0.81 | LMNA (0.58) | KMT2ALMNASMN1; SMN2NPSR1IDO1 | |
| SCHEMBL18893491 | 0.79 | LMNA (0.45) | KMT2ALMNASMN1; SMN2IDO1MEN1 | |
| SCHEMBL25866513 | 0.79 | ALDH1A1 (0.46) | KMT2AALOX15LMNASMN1; SMN2KDM4E | |
| SCHEMBL18815188 | 0.78 | IDO1 (0.39) | IDO1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3252045-B1 | CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS | ABBVIE INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-9656956-B2 | Benzene, pyridine, and pyridazine derivatives | ESANEX, INC. (US) | 2017-05-23 | — | — | US | disclosed |