Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17729351 | 0.83 | APP (0.53) | APPMAPTKCNH2CYP3A4CYP2C9 | |
| SCHEMBL9763745 | 0.79 | APP (0.48) | APPMAPTKCNH2CYP1A2CYP3A4 | |
| SCHEMBL4622686 | 0.77 | KCNH2 (0.41) | MAPTKCNH2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10362542 | 0.77 | LMNA (0.49) | KCNH2MEN1KMT2AMMP2MMP12 | |
| SCHEMBL1276464 | 0.76 | CYP1A2 (0.56) | APPMAPTKCNH2CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL25239520 | 0.74 | BLM (0.64) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11459291 | 0.74 | APP (0.59) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL864945 | 0.74 | APP (1.00) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9611200 | 0.74 | APP (1.00) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9834499 | 0.74 | APP (0.53) | APPKCNH2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113262564-A | Surface modified filter media | 霍林斯沃思和沃斯有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111939678-A | Pre-coalesced multi-layer filter media | 霍林斯沃思和沃斯有限公司 | 2020-11-17 | — | — | CN | disclosed |
| US-10414866-B2 | Troger's base polymers having intrinsic microporosity | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-09-17 | — | — | US | disclosed |
| US-20180319937-A1 | HIGH SOLIDS POLYCARBOXYLATE SYNTHESIS FOR CEMENT SUPERPLASTICIZERS | DOW GLOBAL TECHNOLOGIES LLC | 2018-11-08 | — | — | US | disclosed |
| WO-2017091357-A1 | TROGER'S BASE POLYMERS HAVING INTRINSIC MICROPOROSITY | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-06-01 | — | — | WO | disclosed |