Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623625 | 0.90 | HTT (0.37) | KCNH2PYCR1MMP2MMP12HTR2A | |
| SCHEMBL9209153 | 0.88 | KCNH2 (0.41) | KCNH2PYCR1MMP2MMP12LMNA | |
| SCHEMBL18894300 | 0.77 | APP (0.56) | KCNH2MMP2MMP12CYP1A2CYP3A4 | |
| SCHEMBL10362542 | 0.77 | LMNA (0.49) | KCNH2MMP2MMP12CYP2A6HTR2A | |
| SCHEMBL508102 | 0.76 | PYCR1 (0.41) | KCNH2PYCR1CYP2A6HTR2AMAOB | |
| SCHEMBL1276464 | 0.76 | CYP1A2 (0.56) | KCNH2MMP2MMP12HTR2AHTR2C | |
| SCHEMBL81530 | 0.74 | MMP2 (0.47) | PYCR1MMP2MMP12CYP2A6MAOB | |
| SCHEMBL4621099 | 0.74 | PYCR1 (0.40) | PYCR1MMP2MMP12CYP2A6MAOB | |
| SCHEMBL22122003 | 0.74 | CYP2C19 (0.60) | PYCR1CYP2A6HTR2AMAOBMAOA | |
| SCHEMBL797749 | 0.74 | FFAR1 (0.40) | PYCR1MMP2MMP12CYP2A6MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-6586554-B1 | Polyarylene and method for production thereof | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-07-01 | — | — | US | disclosed |