Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.41 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.41 |
| ▸ | LIG1 | P18858 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669636 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL1889645 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL7068224 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| Zinc Ion SCHEMBL2788244 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL18259145 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL1426602 | 0.97 | LIG1 (0.67) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL3798396 | 0.86 | KDM4E (0.71) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL9696302 | 0.86 | LIG1 (0.71) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL40310 | 0.84 | LIG1 (0.69) | LIG1KDM4ECYP3A4ADRB2ADRB1 | |
| SCHEMBL29519569 | 0.84 | LIG1 (0.69) | LIG1KDM4ECYP3A4ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141674-B | Extreme pressure antiwear lubricating oil and preparation method thereof | 贝源新材料科技(广东)有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-115141674-A | Extreme pressure antiwear lubricating oil and preparation method thereof | 贝源新材料科技(广东)有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-116515543-B | High-dispersion stable lubricating oil metal detergent and preparation method thereof | 湖南鸿福实业有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116515543-A | High-dispersion stable lubricating oil metal detergent and preparation method thereof | 湖南鸿福实业有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116478748-A | Preparation method of neutral salicylate detergent | 中国石油天然气股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115141674-B | Extreme pressure antiwear lubricating oil and preparation method thereof | 贝源新材料科技(广东)有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115141674-A | Extreme pressure antiwear lubricating oil and preparation method thereof | 贝源新材料科技(广东)有限公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-112574721-A | Multi-effect environment-friendly glycol type automobile cooling liquid and preparation method thereof | 江苏艾德露环保科技有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-112538339-A | Engine coolant | 山东泰和水处理科技股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| EP-1819804-B1 | Emulsifier blends for lubricating oils | CHEMTURA CORP (US) | 2011-02-16 | — | — | EP | disclosed |
| US-7585822-B2 | blend of sodium sulfonate emulsifier selected from sodium synthethic sulfonates, sodium petroleum sulfonates or blends and at least one monoalkyl linear C14-C18 salicylate sodium salt; for preparing water-miscible concentrates of lubricating oils | CROMPTON CORPORATION (US) | 2009-09-08 | — | — | US | disclosed |
| EP-0207560-B1 | GASOLINE COMPOSITION | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-04-01 | — | — | EP | disclosed |
| US-5064545-A | REACTING OIL SOLUBLE ORGANIC ACIDS WITH METAL OXIDES OR HYDROXIDES, BORIC ACID, AND PROMOTERS | THE LUBRIZOL CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0295278-B1 | A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION | The Lubrizol Corporation (US) | 1991-05-08 | — | — | EP | disclosed |
| US-4987273-A | REVERSE OSMOSIS | SHELL OIL COMPANY (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0370555-A2 | A process for the separation of a phenol | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-05-30 | — | — | EP | disclosed |
| EP-0295278-A1 | A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION. | LUBRIZOL CORP (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4765800-A | SUCCINIC ACID DERIVATIVE WITH HYDROCARBON SUBSTITUENT AS ADDITIVE | SHELL OIL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| WO-1988004685-A2 | A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION | THE LUBRIZOL CORPORATION (US) | 1988-06-30 | — | — | WO | disclosed |
| EP-0207560-A1 | Gasoline composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-01-07 | — | — | EP | disclosed |