Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4155295 | 0.81 | POLB (0.67) | POLBLMNASMN1; SMN2USP2TSHR | |
| SCHEMBL18901678 | 0.79 | CCR2 (0.44) | POLBLMNASMN1; SMN2USP2TSHR | |
| SCHEMBL18901634 | 0.78 | MAPT (0.50) | POLBLMNACCR2KCNH2TRPV1 | |
| SCHEMBL3327045 | 0.78 | IDO1 (0.57) | POLBLMNASMN1; SMN2TSHRCCR2 | |
| SCHEMBL34469409 | 0.77 | LMNA (0.57) | POLBLMNASMN1; SMN2USP2TSHR | |
| SCHEMBL18901823 | 0.75 | CYP11B2 (0.40) | USP2TSHRSMYD3 | |
| SCHEMBL18901677 | 0.75 | CCR2 (0.56) | POLBPIK3CDPIK3CACCR2KCNH2 | |
| SCHEMBL22494771 | 0.74 | TDP1 (0.56) | LMNASMN1; SMN2USP2TSHRTDP1 | |
| SCHEMBL4296524 | 0.74 | CCR2 (0.61) | CCR2KCNH2 | |
| SCHEMBL13361867 | 0.74 | CCR2 (0.61) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |