SCHEMBL1890227

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17787666	0.92	PARP1 (0.49)	PARP1PTGESHDAC3HDAC7HDAC10
	SCHEMBL1892116	0.89	PIK3C2B (0.52)	PARP1PTGESPIK3C2BPIK3CDPIK3R1
	SCHEMBL12662375	0.83	PTGES (0.46)	PARP1PTGESPIK3C2BPIK3R1HDAC3
	SCHEMBL12662376	0.81	PTGES (0.51)	PARP1PTGESMAPK9MAPK10RAF1
	SCHEMBL12662378	0.81	PTGES (0.44)	PARP1PTGESPIK3C2BPIK3CDPIK3R1
	SCHEMBL1688037	0.81	ALDH1A1 (0.44)	PARP1PTGESPIK3C2BPIK3CDPIK3R1
	SCHEMBL1889697	0.81	LMNA (0.50)	PARP1PTGESHDAC3HDAC7HDAC10
	SCHEMBL1632944	0.77	ALDH1A1 (0.47)	PIK3CDPIK3CBIGF1RMAPTKDM4E
	SCHEMBL1633300	0.76	PIK3CB (0.45)	PIK3C2BPIK3CDPIK3CBIGF1RCYP1A2
	SCHEMBL1633176	0.76	ALDH1A1 (0.44)	PIK3C2BPIK3CDPIK3CBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.