SCHEMBL1890430

SCHEMBL1890430

CC(C)COC(=O)NC(NC(=O)OCC(C)C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
TSHR P16473 2/20 0.50
LMNA P02545 2/20 0.48
CNR2 P34972 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
MAPK1 P28482 1/20 0.46
HPGD P15428 1/20 0.45
KDM4E B2RXH2 1/20 0.45
KMT2A Q03164 1/20 0.44
HTT P42858 2/20 0.44
ALOX15 P16050 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6436027 0.84 ATM (0.59) ALDH1A1TSHRLMNAHPGDKDM4E
SCHEMBL6436022 0.84 ATM (0.59) ALDH1A1TSHRLMNAHPGDKDM4E
SCHEMBL962468 0.83 SMN1; SMN2 (0.63) LMNACNR2SMN1; SMN2MAPK1HPGD
SCHEMBL9665752 0.78 KMT2A (0.53) ALDH1A1TSHRCNR2HPGDKMT2A
SCHEMBL7279578 0.78 MAPT (0.46) ALDH1A1TSHRLMNAHPGDKDM4E
SCHEMBL14654947 0.78 NPC1 (0.63) ALDH1A1TSHRLMNAKDM4EKMT2A
SCHEMBL14636230 0.78 NPC1 (0.63) ALDH1A1TSHRLMNAKDM4EKMT2A
SCHEMBL13387483 0.78 SMN1; SMN2 (0.65) TSHRLMNACNR2SMN1; SMN2MAPK1
SCHEMBL7279722 0.77 GPR88 (0.42) ALDH1A1TSHRLMNAKDM4EHTT
SCHEMBL7270481 0.76 GPR88 (0.41) ALDH1A1TSHRLMNAHPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2493850-A1 METHOD FOR THE COMBINED PRODUCTION OF DIISOCYANATES AND/OR POLYISOCYANATES AND GLYCOLS BASF SE (DE) 2012-09-05 EP disclosed
WO-2011051314-A1 METHOD FOR THE COMBINED PRODUCTION OF DIISOCYANATES AND/OR POLYISOCYANATES AND GLYCOLS BASF SE (DE) 2011-05-05 WO disclosed