Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13506014 | 0.86 | LMNA (0.60) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL11697695 | 0.84 | MMP8 (0.49) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL9371027 | 0.84 | MEN1 (0.58) | GAAMMP8ATMMAPTKMT2A | |
| SCHEMBL13387483 | 0.83 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPK1CNR2LMNANPC1 | |
| SCHEMBL24661545 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL1200738 | 0.83 | ATM (0.62) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL1890430 | 0.83 | ALDH1A1 (0.50) | SMN1; SMN2MAPK1CNR2LMNAHTT | |
| SCHEMBL1200775 | 0.83 | ATM (0.62) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL1200736 | 0.83 | ATM (0.62) | SMN1; SMN2MAPK1GAAMMP8ATM | |
| SCHEMBL9359270 | 0.83 | ATM (0.50) | SMN1; SMN2MAPK1GAAMMP8ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846970-B2 | Metal carbamates formed from tolylenediamines | BASF SE (DE) | 2014-09-30 | — | — | US | claimed |
| US-20130231495-A1 | METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES | BASF SE (DE) | 2013-09-05 | — | — | US | claimed |
| EP-2265573-B1 | METAL CARBAMATES COMPOSED OF TOLYLENEDIAMINES | BASF SE (DE) | 2011-10-12 | — | — | EP | claimed |
| US-20110004012-A1 | METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES | BASF SE (DE) | 2011-01-06 | — | — | US | claimed |
| EP-0520273-A2 | Process for the preparation of bis(ethoxycarbonylamino) toluols and their use in the preparation of diisocyanato toluols | BAYER AG (DE) | 1992-12-30 | — | — | EP | claimed |
| JP-5201953-A | — | — | None | — | — | JP | disclosed |
| CN-103492364-A | Method for manufacturing tolylene diisocyanate | MITSU CHEMICALS INC | 2014-01-01 | — | — | CN | disclosed |
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | REPSOL YPF, S.A. (ES) | 2009-03-26 | — | — | US | disclosed |
| EP-2036884-A1 | Process for producing fluorinated isocyanates and carbamates | REPSOL YPF S.A. (ES) | 2009-03-18 | — | — | EP | disclosed |
| US-5646328-A | Process for removing by-products from diurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-08 | — | — | US | disclosed |
| JP-H05201953-A | PRODUCTION OF BIS-(ETHOXYCARBONYL-AMINO)-TOLUENE AND PROCESS FOR PRODUCING DIISOCYANATETOLUENE THEREFROM | BAYER AG | 1993-08-10 | — | — | JP | disclosed |
| EP-0520273-A2 | Process for the preparation of bis(ethoxycarbonylamino) toluols and their use in the preparation of diisocyanato toluols | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0520273-A2 | Process for the preparation of bis(ethoxycarbonylamino) toluols and their use in the preparation of diisocyanato toluols | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0027952-A1 | Process for preparing N,O-disubstituted urethanes | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082588-A1 | Process for producing fluorinated carbamates and isocyanates | SRM, CA4, PRMT3 | SMN1; SMN2 2866/4885MAPK1 2014/4885GAA 2784/4885 |
| US-20130231495-A1 | METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES | CHRM1, CARM1, TCP1 | SMN1; SMN2 3161/4885MAPK1 2882/4885GAA 1943/4885 |
| US-20110004012-A1 | METAL CARBAMATES FORMED FROM TOLYLENEDIAMINES | CHRM1, CARM1, TCP1 | SMN1; SMN2 3161/4885MAPK1 2882/4885GAA 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.