Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 7/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905460 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL10601858 | 0.81 | RELA (0.68) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL10601861 | 0.81 | RELA (0.68) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL18911077 | 0.81 | RELA (0.68) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL18905531 | 0.80 | RELA (0.47) | ALDH1A1LMNACYP3A4TP53KDM4E | |
| SCHEMBL9860997 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL9860994 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL9860945 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL13757288 | 0.78 | AHR (0.62) | ALDH1A1LMNACYP3A4TP53TSHR | |
| SCHEMBL12203894 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNACYP3A4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |