Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18912877 | 0.92 | HTT (0.33) | HTTTP53SMN1; SMN2NPSR1LMNA | |
| SCHEMBL18912876 | 0.78 | HSD11B1 (0.37) | HTTLMNA | |
| SCHEMBL13216610 | 0.76 | ALDH1A1 (0.39) | HTTTP53SMN1; SMN2NPSR1LMNA | |
| SCHEMBL3020896 | 0.76 | ALDH1A1 (0.39) | HTTTP53SMN1; SMN2NPSR1LMNA | |
| SCHEMBL7857014 | 0.74 | HSD11B1 (0.34) | HTTLMNA | |
| SCHEMBL18906496 | 0.70 | — | — | |
| SCHEMBL353233 | 0.69 | HSD11B1 (0.43) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16249890 | 0.67 | HSD11B1 (0.42) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16249613 | 0.65 | HSD11B1 (0.39) | LMNAALDH1A1 | |
| SCHEMBL16522346 | 0.63 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170153549-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION HAVING ORGANIC GROUP HAVING ALIPHATIC POLYCYCLIC STRUCTURE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-06-01 | — | — | US | disclosed |