Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18907696 | 0.86 | FAAH (0.38) | PPARGL3MBTL1MAPTTDP1 | |
| SCHEMBL18972304 | 0.86 | SLC6A9 (0.43) | SLC6A9SLC6A5PPARGFFAR4FFAR1 | |
| SCHEMBL18821425 | 0.85 | SLC6A9 (0.42) | SLC6A9SLC6A5PPARGFFAR4FFAR1 | |
| SCHEMBL18914272 | 0.84 | ALOX15 (0.36) | FFAR4FFAR1KDM4E | |
| SCHEMBL18907708 | 0.81 | SLC6A9 (0.42) | SLC6A9SLC6A5FFAR4FFAR1MRGPRX4 | |
| SCHEMBL18907703 | 0.81 | SLC6A9 (0.42) | SLC6A9SLC6A5FFAR4FFAR1MRGPRX4 | |
| SCHEMBL18961591 | 0.80 | SMN1; SMN2 (0.35) | FFAR4FFAR1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL18908199 | 0.75 | PTGDR2 (0.36) | SLC6A9SLC6A5FFAR4FFAR1CYP2C19 | |
| SCHEMBL28332606 | 0.74 | SLC6A9 (0.52) | SLC6A9SLC6A5FFAR4FFAR1MRGPRX4 | |
| SCHEMBL18907913 | 0.74 | CNR2 (0.37) | PPARGL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800791-B2 | Triazole ACC inhibitors and uses thereof | GILEAD APOLLO, LLC (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190241582-A1 | Triazole ACC inhibitors and uses thereof | Nimbus Apollo, Inc. | 2019-08-08 | — | — | US | disclosed |
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. | 2017-06-15 | — | — | US | disclosed |
| WO-2017091617-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241582-A1 | Triazole ACC inhibitors and uses thereof | ACACA, ACACB, ACAT1 | SLC6A9 3707/4885SLC6A5 3214/4885PPARG 371/4885 |
| US-10800791-B2 | Triazole ACC inhibitors and uses thereof | ACACA, ACACB, ACAT1 | SLC6A9 3707/4885SLC6A5 3214/4885PPARG 371/4885 |
| US-20170166584-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT1 | SLC6A9 3707/4885SLC6A5 3214/4885PPARG 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.