Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25865236 | 0.84 | SIGMAR1 (0.40) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9824225 | 0.79 | OPRD1 (0.35) | SIGMAR1S1PR1S1PR3S1PR5 | |
| SCHEMBL9824881 | 0.78 | HRH3 (0.33) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9824818 | 0.75 | OPRD1 (0.33) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12011342 | 0.74 | HRH3 (0.37) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL12011344 | 0.74 | HRH3 (0.37) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9824140 | 0.74 | CHRM2 (0.37) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL14509625 | 0.74 | ALOX15 (0.35) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9824822 | 0.73 | S1PR1 (0.37) | SIGMAR1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL9824576 | 0.73 | OPRD1 (0.36) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152213-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152213-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | SIGMAR1 1262/4885HTR1D 3519/4885HTR1B 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.