Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23168991 | 0.79 | PRKDC (0.43) | PRKDCP2RX7ALDH1A1L3MBTL1LMNA | |
| SCHEMBL18914541 | 0.76 | ALDH1A1 (0.47) | PRKDCP2RX7ALDH1A1L3MBTL1LMNA | |
| SCHEMBL15831849 | 0.76 | PRKDC (0.47) | PRKDCP2RX7ALDH1A1L3MBTL1LMNA | |
| SCHEMBL4052455 | 0.72 | PKM (0.46) | ALDH1A1L3MBTL1LMNASMN1; SMN2HPGD | |
| SCHEMBL5793530 | 0.71 | NCF1 (0.45) | PRKDCALDH1A1LMNASMN1; SMN2HPGD | |
| SCHEMBL3885064 | 0.70 | KMT2A (0.53) | PRKDCALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL16577085 | 0.69 | HTR1A (0.45) | PRKDCP2RX7LMNACYP2C9CYP1A2 | |
| SCHEMBL670502 | 0.69 | AGXT (0.64) | ALDH1A1L3MBTL1LMNACYP2C9MAPT | |
| SCHEMBL6301740 | 0.69 | KDM4A (0.38) | ALDH1A1L3MBTL1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL5643020 | 0.69 | TAAR1 (0.44) | ALDH1A1L3MBTL1POLBHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017090743-A1 | NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST | 田辺三菱製薬株式会社 | 2017-06-01 | — | — | WO | disclosed |