Dipyridyl

Dipyridyl

SCHEMBL18917065

O=C1CCC(=O)N1O.O=C1CCC(=O)N1O.[Ru+2].c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1.c1ccc(-c2ccccn2)nc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.52
LMNA P02545 3/20 0.52
CCR1 P32246 3/20 0.52
CCR5 P51681 3/20 0.52
CCR8 P51685 3/20 0.52
P4HTM Q9NXG6 2/20 0.52
CYP1A2 P05177 1/20 0.52
POLB P06746 1/20 0.52
METAP1 P53582 1/20 0.52
BLM P54132 1/20 0.52
HIF1A Q16665 1/20 0.52
DOHH Q9BU89 1/20 0.52
ALOX15 P16050 3/20 0.45
TP53 P04637 3/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL687954 0.98 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL18920847 0.98 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL8655285 0.96 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL8655290 0.96 KDM4E (0.52) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28599019 0.81 TGFBR1 (0.41) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL28137298 0.79 KDM4E (0.54) KDM4ELMNACCR1CCR5CCR8
SCHEMBL18191184 0.79 EHMT2 (0.59) LMNAPOLBSMN1; SMN2L3MBTL1NPC1
2-Picolinic Acid SCHEMBL994022 0.77 L3MBTL1 (0.67) KDM4ELMNAP4HTMSMN1; SMN2L3MBTL1
Dipyridyl SCHEMBL2349545 0.74 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL501794 0.74 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3384288-B1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS ROCHE DIAGNOSTICS GMBH (DE) 2024-01-10 EP disclosed
US-11320423-B2 Method for reduction of interferences in immunoassays ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2022-05-03 US disclosed
US-20180348211-A1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2018-12-06 US disclosed
EP-3384288-A1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS Roche Diagnostics GmbH (DE) 2018-10-10 EP disclosed
WO-2017093271-A1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS ROCHE DIAGNOSTICS GMBH (DE) 2017-06-08 WO disclosed
EP-3176580-A1 METHOD FOR REDUCTION OF INTERFERENCES IN IMMUNOASSAYS Roche Diagnostics GmbH (DE) 2017-06-07 EP disclosed