Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257741 | 0.83 | SLC6A3 (0.50) | MAPTSIGMAR1SLC6A3KMT2AMEN1 | |
| SCHEMBL17465576 | 0.82 | L3MBTL1 (0.65) | MAPTL3MBTL1SIGMAR1SLC6A3HTT | |
| SCHEMBL28191143 | 0.82 | L3MBTL1 (0.65) | MAPTL3MBTL1SIGMAR1SLC6A3HTT | |
| SCHEMBL5269597 | 0.80 | SMN1; SMN2 (0.61) | MAPTL3MBTL1SIGMAR1KMT2AMEN1 | |
| SCHEMBL5272038 | 0.80 | SMN1; SMN2 (0.61) | MAPTL3MBTL1SIGMAR1KMT2AMEN1 | |
| SCHEMBL1162316 | 0.76 | SMN1; SMN2 (0.66) | MAPTSIGMAR1SLC6A3KMT2AMEN1 | |
| SCHEMBL15135599 | 0.76 | SMN1; SMN2 (0.66) | MAPTSIGMAR1SLC6A3KMT2AMEN1 | |
| SCHEMBL5982192 | 0.75 | MEN1 (0.54) | MAPTL3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL27489342 | 0.74 | SLC6A2 (0.58) | MAPTL3MBTL1SIGMAR1SLC6A3HTT | |
| SCHEMBL5981801 | 0.74 | RAB9A (0.54) | MAPTL3MBTL1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | UNIVERSITETET I OSLO (NO) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170158657-A1 | TERTIARY AMINES FOR USE IN THE TREATMENT OF CARDIAC DISORDERS | TNNI3, TNNT2, MYLK2 | MAPT 1807/4885L3MBTL1 2957/4885SIGMAR1 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.