Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 3/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15425872 | 0.83 | KMT2A (0.54) | OPRK1ALPLL3MBTL1ALDH1A1PLA2G1B | |
| SCHEMBL15425876 | 0.83 | KMT2A (0.54) | OPRK1ALPLL3MBTL1ALDH1A1PLA2G1B | |
| SCHEMBL6885993 | 0.77 | SIGMAR1 (0.59) | OPRK1OPRM1OPRD1KCNH2ALPL | |
| SCHEMBL15014563 | 0.76 | CHRM2 (0.58) | OPRK1OPRM1OPRD1KCNH2L3MBTL1 | |
| SCHEMBL4530898 | 0.76 | CHRM2 (0.58) | OPRK1OPRM1OPRD1KCNH2L3MBTL1 | |
| SCHEMBL12463216 | 0.74 | OPRK1 (0.45) | OPRK1ALPLL3MBTL1ENPP2ALDH1A1 | |
| SCHEMBL21120887 | 0.73 | TRPV6 (0.57) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL156415 | 0.72 | ACHE (0.67) | HRH3ALDH1A1MAPT | |
| SCHEMBL19223462 | 0.71 | HRH3 (0.64) | OPRM1OPRD1KCNH2ALPLHRH3 | |
| SCHEMBL18924914 | 0.71 | CXCR6 (0.53) | ALDH1A1CXCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670198-B2 | Nicotinic acetylcholine receptor modulators | ASTRAEA THERAPEUTICS, LLC (US) | 2017-06-06 | — | — | US | disclosed |