Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298817 | 0.87 | PGR (0.40) | NPY5RTRPM8MEN1KMT2ALMNA | |
| SCHEMBL8535379 | 0.82 | HTR2A (0.44) | TRPM8LMNAHTR2AHRH1GLA | |
| SCHEMBL628344 | 0.82 | NR1H2 (0.47) | TRPM8LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL27855089 | 0.82 | NR1H2 (0.47) | TRPM8LMNACHRM2CHRM4CHRM1 | |
| SCHEMBL12292188 | 0.79 | ALDH1A1 (0.43) | NPY5RTRPM8MEN1KMT2ALMNA | |
| SCHEMBL2756116 | 0.78 | HPGD (0.40) | NPY5RTRPM8MEN1KMT2ALMNA | |
| SCHEMBL13179219 | 0.77 | OPRD1 (0.41) | NPY5RTRPM8MEN1KMT2ALMNA | |
| SCHEMBL11929029 | 0.74 | MEN1 (0.47) | MEN1KMT2ALMNAHSD17B10CHRM2 | |
| SCHEMBL23135687 | 0.73 | LMNA (0.52) | MEN1KMT2ALMNAHSD17B10HPGD | |
| SCHEMBL627471 | 0.73 | CYP1A2 (0.41) | LMNAAOC3NR1H2NR1H3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10039754-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170157104-A1 | Anti-Viral Compounds | ABBVIE INC. (US) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170157104-A1 | Anti-Viral Compounds | HAVCR2, EIF2AK2, MAVS | NPY5R 4862/4885TRPM8 3749/4885MEN1 4681/4885 |
| US-10039754-B2 | Anti-viral compounds | HAVCR2, EIF2AK2, MAVS | NPY5R 4862/4885TRPM8 3749/4885MEN1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.