⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886838 | 0.83 | — | — | |
| SCHEMBL2955173 | 0.82 | GABBR2 (0.31) | — | |
| SCHEMBL1887525 | 0.80 | LMNA (0.35) | — | |
| SCHEMBL2956005 | 0.79 | CTSK (0.36) | — | |
| SCHEMBL1887582 | 0.78 | MEN1 (0.33) | — | |
| SCHEMBL1895016 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL1888617 | 0.76 | PRKCA (0.34) | — | |
| SCHEMBL3894814 | 0.76 | PRKCA (0.30) | — | |
| SCHEMBL1882814 | 0.76 | CTSK (0.34) | — | |
| SCHEMBL9197708 | 0.74 | TDP1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935686-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. (US) | 2011-05-03 | — | — | US | disclosed |
| US-20090124582-A1 | Acyloxyalkyl Carbamate Prodrugs, Methods of Synthesis, and Use | XENOPORT, INC. (US) | 2009-05-14 | — | — | US | disclosed |
| US-7494985-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. (US) | 2009-02-24 | — | — | US | disclosed |
| US-20060111325-A1 | Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use | XENOPORT, INC. | 2006-05-25 | — | — | US | disclosed |