Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 8/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 4/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | LTK | P29376 | 2/20 | 1.00 |
| ▸ | CDK8 | P49336 | 2/20 | 1.00 |
| ▸ | PRKX | P51817 | 2/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 2/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 2/20 | 1.00 |
| ▸ | STK3 | Q13188 | 2/20 | 1.00 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 1.00 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Y-27632 SCHEMBL342816 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL598993 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL28416532 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1980406 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL190356 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL20333114 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL30286315 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL819701 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2834049 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2796890 | 0.99 | ROCK2 (0.97) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10655105-B2 | Method for proliferation of pancreatic progenitor cells | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-05-19 | — | — | US | claimed |
| EP-4397749-A1 | KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-07-10 | — | — | EP | disclosed |
| US-20240124846-A1 | GROWTH INHIBITOR | Orizuru Therapeutics, Inc. (JP) | 2024-04-18 | — | — | US | disclosed |
| EP-3450546-B1 | SKELETAL MUSCLE PRECURSOR CELLS AND PRODUCTION METHOD FOR SKELETAL MUSCLE CELLS | TAKEDA PHARMACEUTICALS CO (JP) | 2024-03-13 | — | — | EP | disclosed |
| WO-2024014497-A1 | FIBRIN GEL SHEET FOR CELL TRANSPLANTATION | オリヅルセラピューティクス株式会社 | 2024-01-18 | — | — | WO | disclosed |
| EP-4293105-A1 | MATURATION AGENT | Orizuru Therapeutics, Inc. (JP) | 2023-12-20 | — | — | EP | disclosed |
| WO-2023210578-A1 | MATURING AGENT HAVING BOTH OF ALK5 INHIBITORY ACTIVITY AND CDK8/19 INHIBITORY ACTIVITY | オリヅルセラピューティクス株式会社 | 2023-11-02 | — | — | WO | disclosed |
| EP-4249587-A1 | MATURATION AGENT | Orizuru Therapeutics, Inc. (JP) | 2023-09-27 | — | — | EP | disclosed |
| EP-3954436-A1 | METHOD FOR PRODUCING BIOTISSUE-LIKE STRUCTURE | Orizuru Therapeutics, Inc. (JP) | 2022-02-16 | — | — | EP | disclosed |
| US-20210371818-A1 | METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS | OSAKA UNIVERSITY (JP) | 2021-12-02 | — | — | US | disclosed |
| EP-3812456-A1 | GROWTH INHIBITOR | Kyoto University (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-20210060210-A1 | HYDROGEL CAPSULE | KYOTO UNIVERSITY (JP) | 2021-03-04 | — | — | US | disclosed |
| EP-3770253-A1 | HYDROGEL CAPSULE | Kyoto University (JP) | 2021-01-27 | — | — | EP | disclosed |
| US-10655105-B2 | Method for proliferation of pancreatic progenitor cells | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-05-19 | — | — | US | disclosed |
| EP-3178924-B1 | METHOD FOR PROLIFERATION OF PANCREATIC PROGENITOR CELLS | TAKEDA PHARMACEUTICALS CO (JP) | 2019-12-25 | — | — | EP | disclosed |
| US-20190338251-A1 | Skeletal Muscle Precursor Cells and Production Method for Skeletal Muscle Cells | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-11-07 | — | — | US | disclosed |
| US-20180010093-A1 | METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS | OSAKA UNIVERSITY (JP) | 2018-01-11 | — | — | US | disclosed |
| EP-3246394-A1 | METHOD FOR INDUCING DIFFERENTIATION OF CORNEAL EPITHELIAL CELLS FROM PLURIPOTENT STEM CELLS | Osaka University (JP) | 2017-11-22 | — | — | EP | disclosed |
| US-20170233700-A1 | Method for Proliferation of Pancreatic Progenitor Cells | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3178924-A1 | METHOD FOR PROLIFERATION OF PANCREATIC PROGENITOR CELLS | Takeda Pharmaceutical Company Limited (JP) | 2017-06-14 | — | — | EP | disclosed |