Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 8/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 4/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | LTK | P29376 | 2/20 | 1.00 |
| ▸ | CDK8 | P49336 | 2/20 | 1.00 |
| ▸ | PRKX | P51817 | 2/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 2/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 2/20 | 1.00 |
| ▸ | STK3 | Q13188 | 2/20 | 1.00 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 1.00 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Y-27632 SCHEMBL28416532 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL598993 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL190356 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL20333114 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL18935698 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL342816 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL30286315 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2796890 | 0.99 | ROCK2 (0.97) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1554110 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2834049 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 637 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026099481-A1 | METHOD FOR PRODUCING CELLS HAVING AN ACINAR CELL PHENOTYPE | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2026-05-15 | — | — | WO | claimed |
| EP-3350313-B1 | DERIVATION OF LIVER ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS | AGENCY FOR SCIENCE TECH AND RESEARCH ASTARSTAR (SG) | 2025-11-26 | — | — | EP | claimed |
| US-12428623-B2 | Generation of midbrain-specific organoids from human pluripotent stem cells | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2025-09-30 | — | — | US | claimed |
| EP-4602150-A1 | A SCALABLE METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIUM (RPE) CELLS | Eyestem Research Private Limited (IN) | 2025-08-20 | — | — | EP | claimed |
| US-20250241964-A1 | SCALABLE METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIUM (RPE) CELLS | EYESTEM RESEARCH PRIVATE LIMITED (IN) | 2025-07-31 | — | — | US | claimed |
| US-20250243467-A1 | BONE MARROW ORGANOIDS PRODUCED FROM INDUCED PLURIPOTENT STEM CELLS AND USES OF THESE ORGANOIDS | Prism Ingenuity GmbH (DE) | 2025-07-31 | — | — | US | claimed |
| US-12371664-B2 | Medium for direct differentiation of pluripotent stem cell-derived mesenchymal stem cell, method for preparing mesenchymal stem cell by using same, and mesenchymal stem cell prepared thereby | CHA BIOTECH CO., LTD. (KR) | 2025-07-29 | — | — | US | claimed |
| CN-120019141-A | Scalable method for generating Retinal Pigment Epithelial (RPE) cells | 艾视泰研究私人有限公司 | 2025-05-16 | — | — | CN | claimed |
| US-20250154472-A1 | Culture Medium for Expanding Breast Epithelial Stem Cells | KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN (NL) | 2025-05-15 | — | — | US | claimed |
| EP-4504908-A1 | BONE MARROW ORGANOIDS PRODUCED FROM INDUCED PLURIPOTENT STEM CELLS AND USES OF THESE ORGANOIDS | Prism Ingenuity GmbH (DE) | 2025-02-12 | — | — | EP | claimed |
| EP-3047018-A1 | CORNEAL STROMAL KERATOCYTE CULTURE | Singapore Health Services Pte Ltd (SG) | 2016-07-27 | — | — | EP | claimed |
| EP-3043822-A1 | COMPOSITIONS FOR PREPARING CARDIOMYOCYTES | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-07-20 | — | — | EP | claimed |
| US-20160186141-A1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE CARDIOMYOCYTES | The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Glad | 2016-06-30 | — | — | US | claimed |
| EP-3006028-A1 | COMPOSITION FOR REDUCING CELL SENESCENCE COMPRISING RHO-KINASE INHIBITOR AND USE THEREOF | Samsung Electronics Co., Ltd (KR) | 2016-04-13 | — | — | EP | claimed |
| US-20160095864-A1 | COMPOSITION FOR REDUCING CELL SENESCENCE COMPRISING RHO-KINASE INHIBITOR AND USE THEREOF | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-04-07 | — | — | US | claimed |
| US-20160031837-A1 | COMPOUNDS FOR INDUCING PROLIFERATION AND DIFFERENTIATION OF CELLS, AND METHODS OF USE THEREOF | THE BROAD INSTITUTE, INC. (US) | 2016-02-04 | — | — | US | claimed |
| WO-2015041606-A1 | CORNEAL STROMAL KERATOCYTE CULTURE | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2015-03-26 | — | — | WO | claimed |
| WO-2015038704-A1 | COMPOSITIONS FOR PREPARING CARDIOMYOCYTES | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2015-03-19 | — | — | WO | claimed |
| US-8883502-B2 | Expandable cell source of neuronal stem cell populations and methods for obtaining and using them | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-11 | — | — | US | claimed |
| US-20130236436-A1 | EXPANDABLE CELL SOURCE OF NEURONAL STEM CELL POPULATIONS AND METHODS FOR OBTAINING AND USNIG THEM | ZHANG KANG (US) | 2013-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160186141-A1 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE CARDIOMYOCYTES | MYLK2, TNNI3, TNNT2 | ROCK2 90/4885ROCK1 186/4885PKN2 1630/4885 |
| US-20160031837-A1 | COMPOUNDS FOR INDUCING PROLIFERATION AND DIFFERENTIATION OF CELLS, AND METHODS OF USE THEREOF | HGF, HDGF, CD14 | ROCK2 206/4885ROCK1 209/4885PKN2 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.