Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 8/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 4/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | LTK | P29376 | 2/20 | 1.00 |
| ▸ | CDK8 | P49336 | 2/20 | 1.00 |
| ▸ | PRKX | P51817 | 2/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 2/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 2/20 | 1.00 |
| ▸ | STK3 | Q13188 | 2/20 | 1.00 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 1.00 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Y-27632 SCHEMBL28416532 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL190356 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1980406 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL20333114 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL18935698 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL342816 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL30286315 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2796890 | 0.99 | ROCK2 (0.97) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1554110 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2834049 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146991-A1 | COMPOSITION AND METHODS OF AGING-RELATED AGENT SCREENING AND TARGET ANALYSIS | Centre for Translational Stem Cell Biology Limited (CN) | 2026-05-28 | — | — | US | claimed |
| EP-4746704-A2 | METHODS FOR CRYOPRESERVING CELLS FOR MODELING A HUMAN BRAIN OR A HUMAN BLOOD-BRAIN BARRIER | Icahn School of Medicine at Mount Sinai (US) | 2026-05-27 | — | — | EP | claimed |
| EP-4746855-A1 | FORMULATIONS AND USES OF ROCK2 INHIBITORS FOR ALS | Graviton Bioscience BV (NL) | 2026-05-27 | — | — | EP | claimed |
| CN-120400031-B | Endometrium organoid culture method | PEKING UNIVERSITY THIRD HOSPITAL (PEKING UNIVERSITY THIRD CLINICAL MEDICAL COLLEGE) (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-121518621-B | Tumor drug evaluation method based on PBMC and prostate organoids and application thereof | WUXI NO.2 PEOPLE'S HOSPITAL (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122094667-A | Formulations and uses of ROCK2 inhibitors for ALS | — | 2026-05-26 | — | — | CN | claimed |
| CN-121575043-B | Method for inducing pluripotent stem cells to differentiate into ovarian granulosa cells and application thereof | Yunnan Saiyuan Biotechnology Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-113633663-B | Application of EPC derived from induced pluripotent stem cell differentiation in preparation of cerebral apoplexy therapeutic agent | Chengnuo regenerative medical technology (Beijing) Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| WO-2026103625-A1 | METHOD FOR CONSTRUCTING THYMUS ORGANOID AND USE THEREOF | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2026-05-21 | — | — | WO | claimed |
| EP-3576527-B1 | DEVICES FOR TISSUE CRYOPRESERVATION AND RECOVERY | US HEALTH (US) | 2026-05-20 | — | — | EP | claimed |
| US-20100041671-A1 | Methods for treating glaucoma | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2010-02-18 | — | — | US | claimed |
| US-20090029970-A1 | PAIN REMEDY CONTAINING ROCK INHIBITOR | ASTELLAS PHARMA INC. (JP) | 2009-01-29 | — | — | US | claimed |
| EP-1854484-A1 | PAIN REMEDY CONTAINING ROCK INHIBITOR | Astellas Pharma Inc. (JP) | 2007-11-14 | — | — | EP | claimed |
| US-20060052367-A1 | Remedy for glaucoma comprising rho kinase inhibitor and beta-blocker | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2006-03-09 | — | — | US | claimed |
| WO-2005120475-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF BACTERIAL INFECTIONS AND SEPSIS | Technische Universität Dresden (DE) | 2005-12-22 | — | — | WO | claimed |
| EP-1598058-A1 | Cosmetic use of at least one inhibitor of the RhoA kinase production and/or RhoA kinase activation as an agent for loosening the features and/or for relaxing the skin | L'OREAL (FR) | 2005-11-23 | — | — | EP | claimed |
| US-20050245509-A1 | Remedy for glaucoma comprising rho kinase inhibitor and prostaglandins | SANTEN PHARMACECUTICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | claimed |
| US-20050222130-A1 | Inhibitors of RhoA kinase production/activation for relaxing the features of and/or for decontracting the skin | L'OREAL (FR) | 2005-10-06 | — | — | US | claimed |
| EP-1568382-A1 | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND &bgr;-BLOCKER | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | claimed |
| EP-1541151-A1 | REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND PROSTAGLANDINS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | claimed |