Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 8/20 | 1.00 |
| ▸ | ROCK1 | Q13464 | 8/20 | 1.00 |
| ▸ | PKN2 | Q16513 | 4/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 3/20 | 1.00 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 2/20 | 1.00 |
| ▸ | CDK1 | P06493 | 2/20 | 1.00 |
| ▸ | CDK2 | P24941 | 2/20 | 1.00 |
| ▸ | LTK | P29376 | 2/20 | 1.00 |
| ▸ | CDK8 | P49336 | 2/20 | 1.00 |
| ▸ | PRKX | P51817 | 2/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 2/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 2/20 | 1.00 |
| ▸ | STK3 | Q13188 | 2/20 | 1.00 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 1.00 |
| ▸ | BRSK1 | Q8TDC3 | 2/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Y-27632 SCHEMBL28416532 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL598993 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1980406 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL20333114 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL18935698 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL342816 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL30286315 | 1.00 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2796890 | 0.99 | ROCK2 (0.97) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL1554110 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 | |
| Y-27632 SCHEMBL2834049 | 0.99 | ROCK2 (1.00) | ROCK2ROCK1PKN2RPS6KA5LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 750 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049275-A1 | INDUCED STEM CELLS | UNIV MONASH (AU) | 2026-02-19 | — | — | US | claimed |
| US-12371664-B2 | Medium for direct differentiation of pluripotent stem cell-derived mesenchymal stem cell, method for preparing mesenchymal stem cell by using same, and mesenchymal stem cell prepared thereby | CHA BIOTECH CO., LTD. (KR) | 2025-07-29 | — | — | US | claimed |
| US-20250017977-A1 | HEPATOCYTES AND HEPATIC NON-PARENCHYMAL CELLS, AND METHODS FOR PREPARATION THEREOF | THE UNIVERSITY OF TOKYO (JP) | 2025-01-16 | — | — | US | claimed |
| US-20240245668-A1 | AGENT FOR TREATING OR PREVENTING GLAUCOMA INCLUDING A SULFONAMIDE COMPOUND AND ANOTHER DRUG | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2024-07-25 | — | — | US | claimed |
| EP-3334820-B1 | INDUCED EXTENDED PLURIPOTENT STEM CELLS, METHODS OF MAKING AND USING | BEIHAO STEM CELL AND REGENERATIVE MEDICINE RES INSTITUTE CO LTD (CN) | 2024-05-15 | — | — | EP | claimed |
| WO-2024079755-A1 | A SCALABLE METHOD FOR PRODUCING RETINAL PIGMENT EPITHELIUM (RPE) CELLS | EYESTEM RESEARCH PRIVATE LIMITED (IN) | 2024-04-18 | — | — | WO | claimed |
| EP-3372673-B1 | METHOD FOR PRODUCING CEREBELLAR PROGENITOR TISSUE | RIKEN (JP) | 2023-12-13 | — | — | EP | claimed |
| US-11839618-B2 | Agent for promoting corneal endothelial cell adhesion | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2023-12-12 | — | — | US | claimed |
| EP-4251739-A1 | INDUCED STEM CELLS | Monash University (AU) | 2023-10-04 | — | — | EP | claimed |
| CN-116761882-A | Inducible stem cells | 莫纳什大学 | 2023-09-15 | — | — | CN | claimed |
| US-6649625-B2 | Agent for prophylaxis and treatment of glaucoma | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2003-11-18 | — | — | US | claimed |
| US-20030165576-A1 | Antitumor effect potentiators | MITSUBISHI PHARMA CORPORATION (JP) | 2003-09-04 | — | — | US | claimed |
| US-20030125351-A1 | Agent for prophylaxis and treatment of glaucoma | AZUMA MITSUYOSHI (JP) | 2003-07-03 | — | — | US | claimed |
| US-20030096843-A1 | Preventives/remedies for kidney diseases | MITSUBISHI PHARMA CORPORATION (JP) | 2003-05-22 | — | — | US | claimed |
| EP-1295607-A1 | ANTITUMOR EFFECT POTENTIATORS | Mitsubishi Pharma Corporation (JP) | 2003-03-26 | — | — | EP | claimed |
| EP-1177796-A1 | PREVENTIVES/REMEDIES FOR LIVER DISEASES | Mitsubishi Pharma Corporation (JP) | 2002-02-06 | — | — | EP | claimed |
| EP-1174150-A1 | PREVENTIVES/REMEDIES FOR ANGIOSTENOSIS | Mitsubishi Pharma Corporation (JP) | 2002-01-23 | — | — | EP | claimed |
| EP-1163910-A1 | PREVENTIVES/REMEDIES FOR INTERSTITIAL PNEUMONIA AND PULMONARY FIBROSIS | Welfide Corporation (JP) | 2001-12-19 | — | — | EP | claimed |
| EP-1034793-A1 | PREVENTIVES/REMEDIES FOR GLAUCOMA | Senju Pharmaceutical Co., Ltd. (JP) | 2000-09-13 | — | — | EP | claimed |
| EP-0370498-A2 | Trans-4-amino(alkyl)-1-pyridylcarbamoylcyclohexane compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-05-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096843-A1 | Preventives/remedies for kidney diseases | RHOA, ROCK1, MMP1 | ROCK2 6/4885ROCK1 2/4885PKN2 808/4885 |
| US-20030125351-A1 | Agent for prophylaxis and treatment of glaucoma | ROCK1, PDE3A, RHOA | ROCK2 10/4885ROCK1 1/4885PKN2 1820/4885 |
| US-20240245668-A1 | AGENT FOR TREATING OR PREVENTING GLAUCOMA INCLUDING A SULFONAMIDE COMPOUND AND ANOTHER DRUG | PTGIS, PTGIR, PTGS1 | ROCK2 539/4885ROCK1 725/4885PKN2 2185/4885 |
| US-20030165576-A1 | Antitumor effect potentiators | RHOT2, ROCK2, CIT | ROCK2 2/4885ROCK1 5/4885PKN2 388/4885 |
| US-20260049275-A1 | INDUCED STEM CELLS | SALL4, SOX18, LEF1 | ROCK2 991/4885ROCK1 345/4885PKN2 2355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.