SCHEMBL18936192

SCHEMBL18936192

N#Cc1cccc2c1OC[CH]O2

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.40
CYP11B1 P15538 15/20 0.35
CYP11B2 P19099 14/20 0.35
ESR2 Q92731 1/20 0.33
TSHR P16473 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18936123 0.82 BRD4 (0.33)
SCHEMBL4046834 0.77 TRPA1 (0.44) TRPA1CYP11B1CYP11B2ESR2TSHR
SCHEMBL17069064 0.76 ABCG2 (0.44) TRPA1CYP11B1CYP11B2TSHRKDM4E
SCHEMBL7128137 0.76 ITGB2 (0.44) TRPA1CYP11B1CYP11B2KDM4E
SCHEMBL18936028 0.73 TRPA1 (0.44) TRPA1CYP11B1CYP11B2ESR2TSHR
SCHEMBL18936117 0.72 MAP3K14 (0.37) ALDH1A1
SCHEMBL8191555 0.72 CA2 (0.40)
SCHEMBL18936102 0.72 CHRNB4 (0.37) ALDH1A1
SCHEMBL14829341 0.72 AHR (0.44)
SCHEMBL9618582 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-19 US disclosed
EP-3178322-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company Limited (JP) 2017-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL OPRM1, TRPA1, L3MBTL3 TRPA1 2/4885CYP11B1 3200/4885CYP11B2 3177/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 TRPA1 2/4885CYP11B1 3200/4885CYP11B2 3177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.