SCHEMBL1893763

SCHEMBL1893763

O=CCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.63
EPHX2 P34913 1/20 0.51
CASP3 P42574 2/20 0.46
FABP7 O15540 2/20 0.44
FABP5 Q01469 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31031847 1.00 KMT2A (0.63) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL571382 0.92 KMT2A (0.67) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL19402658 0.91 KMT2A (0.54) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL31652687 0.91 KMT2A (0.70) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL27928895 0.91 KMT2A (0.70) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL12833414 0.90 KMT2A (0.72) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL26900694 0.89 KMT2A (0.57) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL6364079 0.89 KMT2A (0.70) KMT2AEPHX2CASP3
SCHEMBL7402295 0.88 KMT2A (0.62) KMT2AEPHX2CASP3FABP7FABP5
SCHEMBL13472009 0.87 KMT2A (0.56) KMT2AEPHX2CASP3FABP7FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2185713-A2 PROCESS FOR PREPARING CHIRAL COMPOUNDS Pfizer Products Inc. (US) 2010-05-19 EP claimed
WO-2009019561-A2 PROCESS FOR PREPARING CHIRAL COMPOUNDS PFIZER PRODUCTS INC. (US) 2009-02-12 WO claimed
EP-1893767-A1 PROCESS FOR PRODUCING ATORVASTATIN, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND INTERMEDIATES THEREOF Pfizer, Inc. (US) 2008-03-05 EP claimed
WO-2006134482-A1 PROCESS FOR PRODUCING ATORVASTATIN, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND INTERMEDIATES THEREOF PFIZER INC. (US) 2006-12-21 WO claimed
EP-4725560-A2 ANTI-B7H3 ANTIBODIES FOR THE PREPARATION OF ANTIBODY DRUG CONJUGATES (ADCS) OF KSP INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2026-04-15 EP disclosed
EP-4482583-B1 ZWITTERIONIC ANTIBACTERIAL COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-04-01 EP disclosed
EP-4659809-A2 STEROIDS AND PROTEIN-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-12-10 EP disclosed
EP-3538539-B1 STEROIDS AND PROTEIN-CONJUGATES THEREOF REGENERON PHARMA (US) 2025-08-27 EP disclosed
US-12377159-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-08-05 US disclosed
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS PARION SCIENCES, INC. (US) 2025-04-10 US disclosed
WO-2025072637-A1 OXYGENATED HETEROCYCLIC LSD-1 INHIBITORS AND RELATED METHODS OF USE THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-04-03 WO disclosed
US-20250099600-A1 Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2025-03-27 US disclosed
US-20070179100-A1 Protected monomers ALNYLAM PHARMACEUTICALS, INC. 2007-08-02 US disclosed
WO-2006134482-A1 PROCESS FOR PRODUCING ATORVASTATIN, PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AND INTERMEDIATES THEREOF PFIZER INC. (US) 2006-12-21 WO disclosed
WO-2006066183-A2 NOVEL SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS AXYS PHARMACEUTICALS, INC. (US) 2006-06-22 WO disclosed
US-7030118-B2 Pyrrolotriazinone compounds and their use to treat diseases BRISTOL-MYERS SQUIBB COMPANY (US) 2006-04-18 US disclosed
EP-1519729-A1 PYRROLOTRIAZINONE COMPOUNDS AND THEIR USE TO TREAT DISEASES Bristol-Myers Squibb Company (US) 2005-04-06 EP disclosed
US-20030232832-A1 Nitrogen compounds such as N-(3-Aminopropyl)-N-(1-(3-benzyl-4 -oxo-3,4-dihydropyrrolo(2,1-f)(1,2,4)-triazine-2-yl)-propyl)-4 -methylbenzamide, trifluoroacetic acid salt, used as anticarcinogenic or antiproliferative agents BRISTOL-MYERS SQUIBB COMPANY 2003-12-18 US disclosed
WO-2003099286-A1 PYRROLOTRIAZINONE COMPOUNDS AND THEIR USE TO TREAT DISEASES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-12-04 WO disclosed
WO-1999054321-A1 SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS AVENTIS PHARMA LIMITED (GB) 1999-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250115561-A1 BIPHENYL-SUBSTITUTED EPITHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS CFTR, SCNN1B, SCNN1G KMT2A 3783/4885EPHX2 1658/4885CASP3 1633/4885
US-20030232832-A1 Nitrogen compounds such as N-(3-Aminopropyl)-N-(1-(3-benzyl-4 -oxo-3,4-dihydropyrrolo(2,1-f)(1,2,4)-triazine-2-yl)-propyl)-4 -methylbenzamide, trifluoroacetic acid salt, used as anticarcinogenic or antiproliferative agents CCNB1, NUMA1, CCNA1 KMT2A 325/4885EPHX2 4363/4885CASP3 357/4885
US-20250099600-A1 Active Metabolites of Kinesin Spindle Protein Inhibitor Conjugates KIF18B, KIF18A, KIF5B KMT2A 1659/4885EPHX2 3947/4885CASP3 3888/4885
US-12377159-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 KMT2A 4548/4885EPHX2 2443/4885CASP3 4393/4885
US-20070179100-A1 Protected monomers PCNA, POLN, PARP1 KMT2A 1569/4885EPHX2 4321/4885CASP3 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.