Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ME2 | P23368 | 6/20 | 0.45 |
| ▸ | ME1 | P48163 | 6/20 | 0.45 |
| ▸ | ME3 | Q16798 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7041242 | 0.88 | MAPT (0.68) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL7106841 | 0.81 | KDM4E (0.61) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL8931737 | 0.79 | DRD4 (0.67) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL657027 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL3043144 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL5539457 | 0.77 | ME2 (0.63) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL526167 | 0.77 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL13389789 | 0.77 | MAPT (0.57) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL3988869 | 0.77 | MAPT (0.57) | MAPTALDH1A1KDM4EPKMDRD4 | |
| SCHEMBL13159173 | 0.77 | MAPT (0.63) | MAPTALDH1A1KDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093491-A1 | ANTIMYCOTIC TRIAZOLE COMPOUND | PULMOCIDE LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |