Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18941761 | 0.90 | HPGD (0.51) | HPGDGAAOPRM1MEN1KMT2A | |
| SCHEMBL18942207 | 0.90 | HPGD (0.51) | HPGDGAAOPRM1MEN1KMT2A | |
| SCHEMBL18942104 | 0.89 | SLC6A2 (0.43) | HPGDGAACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18942040 | 0.87 | HPGD (0.54) | HPGDOPRM1MEN1KMT2AKCNK3 | |
| SCHEMBL18942350 | 0.87 | OPRM1 (0.47) | HPGDOPRM1KCNK3ATM | |
| SCHEMBL18941759 | 0.85 | HDAC3 (0.47) | HPGDCYP1A2CYP2C19TSHRHDAC1 | |
| SCHEMBL18942356 | 0.84 | KDM4E (0.56) | HPGDKMT2AATMTSHRHDAC1 | |
| SCHEMBL18942088 | 0.84 | GPR139 (0.45) | HPGDATMGPR139NAMPTNPC1 | |
| SCHEMBL18941691 | 0.84 | HDAC3 (0.47) | HPGDMEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL18942259 | 0.84 | OPRM1 (0.46) | HPGDOPRM1GPR139HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023602-B2 | Hamamelitannin analogues and uses thereof | UNIVERSITEIT GENT (BE) | 2018-07-17 | — | — | US | disclosed |
| US-20170158727-A1 | HAMAMELITANNIN ANALOGUES AND USES THEREOF | UNIVERSITEIT GENT (BE) | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023602-B2 | Hamamelitannin analogues and uses thereof | PIGS, HAMP, HTT | HPGD 190/4885GAA 86/4885CYP1A2 2857/4885 |
| US-20170158727-A1 | HAMAMELITANNIN ANALOGUES AND USES THEREOF | PIGS, HAMP, HTT | HPGD 190/4885GAA 86/4885CYP1A2 2857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.