Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903883 | 0.83 | ADRB2 (0.36) | ADRB2ADRB1ADRB3DRD2 | |
| SCHEMBL19903891 | 0.82 | ADRB2 (0.40) | ADRB2ADRB1DRD2 | |
| SCHEMBL18946707 | 0.81 | ADRB2 (0.37) | ADRB2ADRB1ADRB3DRD2 | |
| SCHEMBL23223709 | 0.75 | ADRB2 (0.39) | ADRB2ADRB1 | |
| SCHEMBL21573495 | 0.71 | ADRB2 (0.42) | ADRB2ADRB1DRD2 | |
| SCHEMBL21573538 | 0.70 | ADRB2 (0.43) | ADRB2ADRB1ADRB3DRD2 | |
| SCHEMBL23223736 | 0.68 | ADRB2 (0.39) | ADRB2ADRB1ADRB3 | |
| SCHEMBL21573489 | 0.66 | ADRB2 (0.40) | ADRB2ADRB1 | |
| SCHEMBL24404566 | 0.66 | ADRB2 (0.40) | ADRB2 | |
| SCHEMBL24404490 | 0.65 | ADRB2 (0.38) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |