Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903891 | 0.89 | ADRB2 (0.40) | ADRB2ADRB1DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL19903887 | 0.83 | ADRB2 (0.32) | ADRB2ADRB1DRD2ADRB3 | |
| SCHEMBL18946707 | 0.83 | ADRB2 (0.37) | ADRB2ADRB1DRD2ADRB3 | |
| SCHEMBL20373657 | 0.77 | ADRB2 (0.40) | ADRB2ADRB1DRD2DRD3 | |
| SCHEMBL21573489 | 0.77 | ADRB2 (0.40) | ADRB2ADRB1 | |
| SCHEMBL21573495 | 0.73 | ADRB2 (0.42) | ADRB2ADRB1DRD2HDAC1 | |
| SCHEMBL21573538 | 0.72 | ADRB2 (0.43) | ADRB2ADRB1DRD2ALDH1A1SMN1; SMN2 | |
| SCHEMBL19903846 | 0.67 | ADRB2 (0.36) | ADRB2ADRB1DRD2ADRB3DRD3 | |
| SCHEMBL20373553 | 0.65 | SMN1; SMN2 (0.44) | ADRB2SMN1; SMN2TDP1 | |
| SCHEMBL22839900 | 0.63 | BACE1 (0.35) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |