Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699075 | 0.89 | LMNA (0.49) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL859 | 0.87 | POLB (0.50) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL5900613 | 0.87 | LMNA (0.48) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL7703155 | 0.86 | LMNA (0.47) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL9199202 | 0.85 | SMYD3 (0.51) | RAB9ASMN1; SMN2NPC1MAPTKDM4E | |
| SCHEMBL14109576 | 0.83 | LMNA (0.45) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL1894879 | 0.83 | LMNA (0.52) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL20503314 | 0.82 | LMNA (0.44) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL6713457 | 0.82 | LMNA (0.44) | LMNARAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL7698241 | 0.81 | LMNA (0.61) | LMNARAB9ASMN1; SMN2NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187894-A | The preparation method of 1 methyl 3 ethyl 4 chlorine 5 pyrazole carboxylic acid ethyl ester | 潍坊鑫诺化工有限公司 | 2016-12-07 | — | — | CN | claimed |
| CN-103556174-A | Synthesis method of ethyl 4-chloro-1-methyl-3-ethyl-5-pyrazolylcarboxylate | UNIV HARBIN SCIENCE & TECH | 2014-02-05 | — | — | CN | claimed |
| CN-103508959-A | Synthesis method of 1-methyl-3-ethyl-5-pyrazolyl ethyl carboxylate | UNIV HARBIN SCIENCE & TECH | 2014-01-15 | — | — | CN | claimed |
| CN-103102307-A | Method for synthesizing tolfenpyrad | UNIV HEILONGJIANG | 2013-05-15 | — | — | CN | claimed |
| US-20260070924-A1 | INDAZOLE MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS INC (US) | 2026-03-12 | — | — | US | disclosed |
| CN-121204042-A | Method for preparing pesticide intermediate by catalyzing multienzyme and coenzyme co-immobilized nanogel | 南京科力硕生物科技有限公司 | 2025-12-26 | — | — | CN | disclosed |
| US-20250143305-A1 | PYRAZOLE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2025-05-08 | — | — | US | disclosed |
| EP-4536225-A1 | INDAZOLE MACROCYCLES AND THEIR USE | Blossomhill Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2025049827-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING PYRAZOLE DERIVATIVES | OSMO LABS, PBC (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-119421709-A | Indazole-containing macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-116063285-B | Substituted pyrimidine (thio) ester compound and application thereof | 沈阳中化农药化工研发有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-119325379-A | Indazole macrocyclic compounds and uses thereof | 荣山医药股份有限公司 | 2025-01-17 | — | — | CN | disclosed |
| US-20130023517-A1 | Therapeutic methods employing substituted piperidines which are CCR3 antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-01-24 | — | — | US | disclosed |
| US-20110015065-A1 | Substituted Sulfonic Acid Amide Compounds | BASF SE (DE) | 2011-01-20 | — | — | US | disclosed |
| EP-2252590-A1 | SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS | BASF SE (DE) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009101082-A1 | SUBSTITUTED SULFONIC ACID AMIDE COMPOUNDS | BASF SE (DE) | 2009-08-20 | — | — | WO | disclosed |
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | NIHON NOHYAKU CO., LTD., (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | NIHON NOHYAKU CO., LTD., (JP) | 2007-01-11 | — | — | US | disclosed |
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | NIHON NOHYAKU CO., LTD., (JP) | 2007-01-11 | — | — | US | disclosed |
| EP-1544202-A1 | NOVEL HERBICIDES, USAGE THEREOF, NOVEL THIENOPYRIMIDINE DERIVATIVES, INTERMEDIATES OF THE SAME, AND PROCESS FOR PRODUCTION THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015065-A1 | Substituted Sulfonic Acid Amide Compounds | STS, NAPA, NAAA | LMNA 3828/4885RAB9A 655/4885SMN1; SMN2 3963/4885 |
| US-20260070924-A1 | INDAZOLE MACROCYCLES AND THEIR USE | NR0B2, NR0B1, ESRRA | LMNA 1639/4885RAB9A 1995/4885SMN1; SMN2 1266/4885 |
| US-20070010402-A1 | Novel herbicides, usage thereof, novel thienopyrimidine derivatives, intermediates of the same, and process for production thereof | DDT, DPYD, DHODH | LMNA 4855/4885RAB9A 4004/4885SMN1; SMN2 4244/4885 |
| US-20250143305-A1 | PYRAZOLE COMPOUND AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | HDAC11, AADAC, CTRL | LMNA 4541/4885RAB9A 399/4885SMN1; SMN2 3563/4885 |
| US-20130023517-A1 | Therapeutic methods employing substituted piperidines which are CCR3 antagonists | CCR3, CCR1, CCR4 | LMNA 4598/4885RAB9A 1934/4885SMN1; SMN2 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.