Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19478609 | 0.86 | GABRA1 (0.52) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL19478530 | 0.80 | GABRA1 (0.39) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL27451548 | 0.80 | HDAC4 (0.45) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL7064844 | 0.77 | GABRA1 (0.73) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL13405958 | 0.74 | GABRA1 (0.57) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL9657114 | 0.73 | GABRA1 (0.61) | GABRA1GABRB2 | |
| SCHEMBL20368215 | 0.73 | GABRA1 (0.47) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL21734367 | 0.73 | GABRA1 (0.67) | HIF1AGABRA1LMNAGABRB2TSHR | |
| SCHEMBL6396467 | 0.72 | ADRB1 (0.39) | HIF1ALMNATSHRHTR2BBLM | |
| SCHEMBL4318572 | 0.72 | GABRA1 (0.55) | HIF1AGABRA1LMNAGABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202372-B2 | Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 2019-02-12 | — | — | US | disclosed |
| US-9796694-B2 | Modulation of bacterial quorum sensing with synthetic ligands | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2017-10-24 | — | — | US | disclosed |
| US-9676763-B2 | Method of treating Ebola | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202372-B2 | Trisubstituted pyrido[2,3-D]pyrimidines, methods for preparing same and therapeutic uses thereof | DPYD, TYMP, RRM2B | HIF1A 2313/4885GABRA1 2475/4885LMNA 3069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.