Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711914 | 0.79 | L3MBTL1 (0.61) | MAPTPOLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL30754625 | 0.78 | L3MBTL1 (0.59) | MAPTPOLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL18701934 | 0.75 | L3MBTL1 (0.57) | MAPTPOLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL1618910 | 0.73 | MAPT (0.53) | MAPTPOLBL3MBTL1PKMALDH1A1 | |
| SCHEMBL29354280 | 0.73 | LMNA (0.76) | MAPTL3MBTL1CA12CA1CA2 | |
| SCHEMBL26010794 | 0.72 | L3MBTL1 (0.67) | L3MBTL1PKMALDH1A1LMNAMAPK1 | |
| SCHEMBL4555736 | 0.72 | L3MBTL1 (0.67) | L3MBTL1PKMALDH1A1LMNAMAPK1 | |
| SCHEMBL7894669 | 0.71 | MAPK9 (0.59) | MAPTPOLBL3MBTL1CA12CA1 | |
| SCHEMBL12761130 | 0.71 | ATM (0.65) | MAPTL3MBTL1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL1348323 | 0.71 | L3MBTL1 (0.66) | MAPTL3MBTL1PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386498-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2018-10-17 | — | — | EP | claimed |
| WO-2017098467-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-06-15 | — | — | WO | claimed |
| US-20180369186-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2018-12-27 | — | — | US | disclosed |
| EP-3386498-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | Jawaharlal Nehru Centre For Advanced Scientific Research (IN) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098467-A1 | METHOD FOR MODULATING AUTOPHAGY AND APPLICATIONS THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-06-15 | — | — | WO | disclosed |