Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711914 | 0.82 | L3MBTL1 (0.61) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL18701934 | 0.78 | L3MBTL1 (0.57) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL18952933 | 0.78 | MAPT (0.70) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL30754639 | 0.77 | PKM (0.67) | LMNASMN1; SMN2PKMPOLBALDH1A1 | |
| SCHEMBL26010794 | 0.75 | L3MBTL1 (0.67) | L3MBTL1LMNAMAPK1SMN1; SMN2PKM | |
| SCHEMBL4555736 | 0.75 | L3MBTL1 (0.67) | L3MBTL1LMNAMAPK1SMN1; SMN2PKM | |
| Hydrochloric Acid SCHEMBL1348323 | 0.74 | L3MBTL1 (0.66) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL30754632 | 0.73 | ALDH1A1 (0.68) | L3MBTL1LMNASMN1; SMN2PKMALDH1A1 | |
| SCHEMBL17175832 | 0.72 | L3MBTL1 (0.55) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT | |
| SCHEMBL4228483 | 0.72 | L3MBTL1 (0.63) | L3MBTL1LMNAMAPK1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720528-A | Oxadiazole sulfonamide compound containing pyrazole structure, and preparation method and application thereof | 贵州大学 | 2024-03-19 | — | — | CN | disclosed |