Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954784 | 0.80 | TP53 (0.43) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18954701 | 0.80 | PARK7 (0.42) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18954601 | 0.80 | PARK7 (0.51) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18954643 | 0.75 | SMAD3 (0.44) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL18955354 | 0.75 | CASP3 (0.48) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL18954756 | 0.75 | KMT2A (0.40) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18954512 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL18954712 | 0.75 | ALDH1A1 (0.47) | PPOXALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL18955235 | 0.74 | L3MBTL1 (0.47) | ALDH1A1KMT2AMEN1MAPTATM | |
| SCHEMBL18954547 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |