Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18954601 | 0.90 | PARK7 (0.51) | PARK7ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18954643 | 0.85 | SMAD3 (0.44) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL18954784 | 0.85 | TP53 (0.43) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL18954547 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18954742 | 0.80 | PPOX (0.39) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL17254677 | 0.77 | PARK7 (0.45) | PARK7ALDH1A1TRPA1ALOX15 | |
| SCHEMBL18955354 | 0.77 | CASP3 (0.48) | ALDH1A1MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL18955235 | 0.76 | L3MBTL1 (0.47) | PARK7ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10430383 | 0.75 | ALDH1A1 (0.64) | PARK7ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18954596 | 0.75 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099695-A1 | N-[(AMINOSULFONYL)PHENYL]-2-(1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDENE)-HYDRAZINECARBOTHIOAMIDE DERIVATIVES FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS | ISTANBUL UNIVERSITESI REKTORLUGU (TR) | 2017-06-15 | — | — | WO | disclosed |