SCHEMBL18958488

SCHEMBL18958488

OB(O)c1ccc2c3ccccc3n(-c3ccc(-c4ccccc4)cc3)c2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.49
HDAC4 P56524 1/20 0.43
KMT2A Q03164 2/20 0.38
TRPV1 Q8NER1 3/20 0.36
PTPN1 P18031 2/20 0.36
IL1R1 P14778 1/20 0.35
AKR1C4 P17516 1/20 0.35
AKR1C3 P42330 1/20 0.35
AKR1C2 P52895 1/20 0.35
AKR1C1 Q04828 1/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HTT P42858 1/20 0.35
RXRA P19793 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19176526 0.93 MGLL (0.51) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL30296541 0.91 MGLL (0.49) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL25672263 0.91 MGLL (0.49) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL29975845 0.91 MGLL (0.49) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL3662775 0.91 MGLL (0.49) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL29789013 0.91 KDM4E (0.60) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL2127336 0.91 KDM4E (0.60) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL29671022 0.91 KDM4E (0.60) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL18958497 0.91 ATM (0.42) MGLLCA1CA2L3MBTL1KDM4E
SCHEMBL18958496 0.90 MGLL (0.40) MGLLCA1CA2L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399336-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-12-14 US disclosed
US-20230399336-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-12-14 US disclosed
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-08-10 US disclosed
US-20210376257-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-12-02 US disclosed
WO-2020071860-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2020-04-09 WO disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD (KR) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399336-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, MANUFACTURING METHOD THEREFOR, AND COMPOSITION FOR ORGANIC LAYER CYP1B1, NOTUM, WEE1 MGLL 1111/4885CA1 3423/4885CA2 4590/4885
US-20210376257-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME NR2E3, CRY2, CRY1 MGLL 891/4885CA1 4598/4885CA2 4243/4885
US-20230250048-A1 NITROGEN-CONTAINING COMPOUND, ELECTRONIC ELEMENT AND ELECTRONIC DEVICE NOS1, NOM1, NCF1 MGLL 3560/4885CA1 2036/4885CA2 2084/4885
US-20170170407-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF OR10J3, OR51E2, ETV6 MGLL 3114/4885CA1 1471/4885CA2 2128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.