Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 6/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488049 | 0.93 | MAPT (0.34) | KDRTP53GAASMN1; SMN2BRAF | |
| SCHEMBL17488024 | 0.89 | NPC1 (0.39) | KDRTP53GAASMN1; SMN2NPC1 | |
| SCHEMBL17488052 | 0.86 | BRAF (0.33) | KDRTP53GAABRAFRAF1 | |
| SCHEMBL18965884 | 0.83 | LMNA (0.39) | TP53GAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL17488323 | 0.82 | MCHR1 (0.40) | KDRTP53POLBGAANPC1 | |
| SCHEMBL17488048 | 0.81 | MCHR1 (0.38) | KDRSMN1; SMN2BRAFRAF1TEK | |
| SCHEMBL18965822 | 0.80 | CYP3A4 (0.45) | KDRSMN1; SMN2NPC1RAB9AMCHR1 | |
| SCHEMBL17488051 | 0.80 | MAPK1 (0.37) | KDRTP53GAASMN1; SMN2NPC1 | |
| SCHEMBL18960449 | 0.80 | GAA (0.42) | TP53POLBGAASMN1; SMN2NPC1 | |
| SCHEMBL18965857 | 0.79 | TP53 (0.37) | TP53POLBGAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166563-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | ALOX5, ALOX15, ALOX12 | KDR 2470/4885TP53 2004/4885POLB 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.