Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1897933 | 0.99 | SLC6A4 (0.45) | SLC6A4PRKD3PRKD1PRKD2SRC | |
| SCHEMBL1897131 | 0.86 | SLC6A4 (0.37) | SLC6A4PRKD3PRKD1PRKD2SRC | |
| Hydrochloric Acid SCHEMBL1897931 | 0.86 | SLC6A4 (0.39) | SLC6A4PRKD3PRKD1PRKD2SRC | |
| SCHEMBL1894485 | 0.84 | TGFBR1 (0.39) | SRCJAK2JAK1TYK2JAK3 | |
| SCHEMBL1898044 | 0.80 | TLR8 (0.42) | SRCTLR7 | |
| SCHEMBL1901666 | 0.75 | ADORA2A (0.41) | TLR7 | |
| SCHEMBL1900995 | 0.74 | HSP90AB1 (0.43) | TLR7 | |
| Hydrochloric Acid SCHEMBL4519043 | 0.73 | KHK (0.41) | SLC6A4KHKMERTKTLR7 | |
| SCHEMBL12667231 | 0.72 | TLR7 (0.42) | SLC6A4PRKD3PRKD1PRKD2KHK | |
| SCHEMBL1898506 | 0.72 | SRC (0.36) | SRCTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943610-B2 | Pyrazolopyridine-1,4-diamines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-17 | — | — | US | disclosed |
| US-20090124611-A1 | Pyrazolopyridine-1,4-Diamines and Analogs Thereof | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124611-A1 | Pyrazolopyridine-1,4-Diamines and Analogs Thereof | IL4, IL2, IL1A | SLC6A4 3188/4885PRKD3 1419/4885PRKD1 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.