Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784347 | 0.84 | ADORA1 (0.40) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL19861815 | 0.78 | ACHE (0.38) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL18750762 | 0.76 | LMNA (0.37) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL12939295 | 0.76 | LMNA (0.37) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL22399607 | 0.76 | ACHE (0.40) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL30587540 | 0.74 | TDP1 (0.42) | LMNAALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11851306 | 0.74 | LMNA (0.35) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL30587581 | 0.74 | TDP1 (0.42) | LMNAALDH1A1CYP3A4MAPK1 | |
| SCHEMBL23633811 | 0.73 | LMNA (0.34) | LMNAADORA1SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL30092676 | 0.72 | CLK1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170166557-A1 | 6-SUBSTITUTED QUINAZOLINONE INHIBITORS | UNIV KANSAS (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166557-A1 | 6-SUBSTITUTED QUINAZOLINONE INHIBITORS | NDUFV3, NDUFV2, NDUFV1 | LMNA 1496/4885ADORA1 4019/4885SMN1; SMN2 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.