Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 5/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18978694 | 0.82 | SMN1; SMN2 (0.33) | GHSRCA1CA9 | |
| SCHEMBL18978622 | 0.70 | LMNA (0.32) | GHSRSOAT1SOAT2CYP3A4CYP2C9 | |
| SCHEMBL14275152 | 0.70 | KDM4E (0.35) | GHSRCACNA1GSOAT1SOAT2KDM4E | |
| SCHEMBL13930055 | 0.69 | KMT2A (0.36) | KDM4EALDH1A1CA1CA9 | |
| SCHEMBL664811 | 0.69 | KMT2A (0.36) | KDM4EALDH1A1CA1CA9 | |
| SCHEMBL18978496 | 0.69 | — | — | |
| SCHEMBL18978511 | 0.66 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL14587066 | 0.65 | CACNA1G (0.44) | CACNA1GSOAT1SOAT2ALDH1A1CYP3A4 | |
| SCHEMBL15292014 | 0.64 | KDM4E (0.30) | KDM4E | |
| SCHEMBL7754367 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-04-20 | — | — | US | disclosed |
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-10-22 | — | — | US | disclosed |
| US-10682374-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190076462-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-03-14 | — | — | US | disclosed |
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-08 | — | — | US | disclosed |
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200330501-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
| US-20230124955-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
| US-20190076462-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
| US-10682374-B2 | Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof | APLNR, NPPA, ARGLU1 | GHSR 135/4885CACNA1G 4843/4885SOAT1 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.