Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.56 |
| ▸ | HTR1D | P28221 | 4/20 | 0.56 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | HTR1B | P28222 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913471 | 0.86 | HTR2A (0.63) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL19067627 | 0.85 | HTR2A (0.61) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL19068711 | 0.83 | HTR2A (0.72) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL699380 | 0.83 | HTR2A (0.58) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL30811419 | 0.83 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL24913231 | 0.83 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL1120488 | 0.83 | HTR2A (0.70) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL15701891 | 0.80 | HTR2A (0.55) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL26054201 | 0.80 | HTR2A (0.55) | HTR2AHTR1DHTR2CHTR1AHTR2B | |
| SCHEMBL7651463 | 0.80 | HTR1D (0.67) | HTR2AHTR1DHTR2CHTR1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-02-08 | — | — | US | disclosed |
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165290-A1 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | HTR2A 3019/4885HTR1D 3373/4885HTR2C 4481/4885 |
| US-20180036333-A9 | AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF | APLNR, NPPA, ARGLU1 | HTR2A 3019/4885HTR1D 3373/4885HTR2C 4481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.