Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24137980 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL25736461 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL21097627 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL20912079 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL18959379 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL23895333 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL21159681 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL23895358 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL21399717 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL23895364 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020200-A1 | Therapeutic compositions and methods of use thereof | HODOSH MILTON | 2007-01-25 | — | — | US | claimed |
| US-7115252-B2 | Therapeutic compositions and methods of use thereof | HODOSH MILTON | 2006-10-03 | — | — | US | claimed |
| US-20030003163-A1 | Therapeutic compositions and methods of use thereof | HODOSH MILTON (US) | 2003-01-02 | — | — | US | claimed |
| EP-0186276-B1 | ORAL HYGIENE COMPOSITION | ICI AMERICAS INC. (US) | 1990-11-22 | — | — | EP | claimed |
| US-4632937-A | MONG-AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS (US) | 1986-12-30 | — | — | US | claimed |
| US-4627979-A | MONOALKYL AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627974-A | CHEWING GUM WITH MONOALKYL AND DIALKYL DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627975-A | MONO AND DIALKYLETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627976-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627980-A | MONOALKYL AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4627978-A | Tooth drop dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-12-09 | — | — | US | claimed |
| US-4610871-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | claimed |
| US-4610872-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | claimed |
| EP-0186276-A2 | Oral hygiene composition | ICI AMERICAS INC. (US) | 1986-07-02 | — | — | EP | claimed |
| US-4585649-A | MONO- AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-04-29 | — | — | US | claimed |
| US-12012416-B2 | Compositions and methods for treating atopic dermatitis | SYTHEON LTD (US) | 2024-06-18 | — | — | US | disclosed |
| US-11903990-B2 | Compositions and methods for treating and removing seborrheic keratoses | STOECKER WILLIAM VAN DOVER (US) | 2024-02-20 | — | — | US | disclosed |
| US-4610871-A | Dentifrice formulation and method of treating teeth, mouth and throat therewith to reduce plaque accumulation and irritation | ICI AMERICAS INC. (US) | 1986-09-09 | — | — | US | disclosed |
| EP-0186276-A2 | Oral hygiene composition | ICI AMERICAS INC. (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4585649-A | MONO- AND DIALKYL ETHERS OF DIANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11903990-B2 | Compositions and methods for treating and removing seborrheic keratoses | CAT, CUTA, GPX1 | THRB 4313/4885LMNA 697/4885MAPT 3500/4885 |
| US-12012416-B2 | Compositions and methods for treating atopic dermatitis | EBP, TSLP, COL14A1 | THRB 4351/4885LMNA 2532/4885MAPT 1795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.