Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25736461 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL21097627 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL20912079 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL1897888 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL18959379 | 1.00 | THRB (0.54) | THRBLMNAMAPTBCHEALDH1A1 | |
| SCHEMBL23895333 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL21159681 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL23895358 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL21399717 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 | |
| SCHEMBL23895364 | 0.87 | ALDH1A1 (0.39) | MAPTBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340599-A1 | AMPK ACTIVATORS | KALLYOPE, INC. | 2022-10-27 | — | — | US | disclosed |
| US-20220002317-A1 | AMPK ACTIVATORS | KALLYOPE, INC. | 2022-01-06 | — | — | US | disclosed |
| WO-2021263039-A1 | AMPK ACTIVATORS | KALLYOPE, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002317-A1 | AMPK ACTIVATORS | PRKAG1, PRKAG2, PRKAA1 | THRB 524/4885LMNA 3696/4885MAPT 874/4885 |
| US-20220340599-A1 | AMPK ACTIVATORS | PRKAG1, PRKAG2, PRKAA1 | THRB 524/4885LMNA 3696/4885MAPT 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.