Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538560 | 0.88 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL28383685 | 0.88 | POLB (0.50) | SMN1; SMN2TSHRMAPTMEN1MAPK1 | |
| SCHEMBL11424711 | 0.86 | TSHR (0.57) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL4397330 | 0.85 | TSHR (0.61) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| Benzophenone SCHEMBL28232881 | 0.85 | MEN1 (0.51) | SMN1; SMN2TSHRMAPTMEN1MAPK1 | |
| SCHEMBL11345555 | 0.84 | ALDH1A1 (0.52) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL27831715 | 0.84 | TSHR (0.59) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL28160008 | 0.83 | ALDH1A1 (0.58) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL10953526 | 0.83 | TSHR (0.57) | SMN1; SMN2TSHRALDH1A1MAPTKDM4E | |
| SCHEMBL9419499 | 0.82 | SRD5A2 (0.58) | ALDH1A1MAPTMAPK1RAB9AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181545-B1 | PROCESS FOR THE PREPARATION OF OSPEMIFENE | SHIONOGI & CO (JP) | 2023-11-01 | — | — | EP | disclosed |
| US-20170297999-A1 | METHOD FOR PRODUCING TRIPHENYLBUTENE DERIVATIVE | Shionogo & Co., Ltd (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3181545-A1 | METHOD FOR PRODUCING TRIPHENYLBUTENE DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2017-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170297999-A1 | METHOD FOR PRODUCING TRIPHENYLBUTENE DERIVATIVE | TERB1, TERT, PAH | SMN1; SMN2 2559/4885TSHR 362/4885ALDH1A1 844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.