SCHEMBL4397330

SCHEMBL4397330

CCOC(=O)c1ccccc1Oc1ccc(C)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
SMN1; SMN2 Q16637 1/20 0.56
ALDH1A1 P00352 4/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 2/20 0.51
RECQL P46063 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPK1 P28482 1/20 0.50
LMNA P02545 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
KDM4E B2RXH2 1/20 0.48
ALK Q9UM73 1/20 0.46
CTNNB1 P35222 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538560 0.90 SMN1; SMN2 (0.68) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL27831715 0.89 TSHR (0.59) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL10953526 0.88 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL11424711 0.88 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL28160008 0.88 ALDH1A1 (0.58) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL28974979 0.87 TSHR (0.74) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL6049205 0.85 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL10930452 0.85 ALDH1A1 (0.58) TSHRSMN1; SMN2ALDH1A1MAPTRECQL
SCHEMBL18979007 0.85 SMN1; SMN2 (0.55) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT
SCHEMBL27254978 0.85 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1829854-B1 PROCESS FOR PRODUCING AROMATIC CARBONATE ASAHI KASEI CHEMICALS CORP (JP) 2013-09-04 EP disclosed
US-7629485-B2 Process for producing aromatic carbonate ASAHI KASEI CHEMICALS CORPORATION (JP) 2009-12-08 US disclosed
US-20080177099-A1 Process for Producing Aromatic Carbonate ASAHI KASEI KABUSHIKI KAISHA (JP) 2008-07-24 US disclosed
EP-1829854-A1 PROCESS FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2007-09-05 EP disclosed
EP-1016648-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES ASAHI CHEMICAL IND (JP) 2003-05-14 EP disclosed
US-6262210-B1 TRANSESTERIFYING DIALKYL CARBONATE, ALKYL ARYL CARBONATE OR MIXTURE WITH AROMATIC MONOHYDROXY COMPOUND IN PRESENCE OF METAL CONTAINING CATALYST TO OBTAIN HIGH BOILING POINT REACTION MIXTURE CONTAINING AROMATIC CARBONATE ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2001-07-17 US disclosed
EP-1016648-A1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 2000-07-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080177099-A1 Process for Producing Aromatic Carbonate DCLK1, ALK, DCLK3 TSHR 4099/4885SMN1; SMN2 4460/4885ALDH1A1 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.