Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18979039 | 1.00 | CES2 (0.40) | CES2PDE2AKIF11CFTRL3MBTL1 | |
| SCHEMBL1758521 | 0.81 | MEN1 (0.41) | PDE2ACYP3A4CYP2D6MAPT | |
| SCHEMBL1758520 | 0.81 | MEN1 (0.41) | PDE2ACYP3A4CYP2D6MAPT | |
| SCHEMBL12535901 | 0.79 | CES2 (0.46) | CES2PDE2ARXRARXRBRXRG | |
| SCHEMBL31135808 | 0.79 | CES2 (0.46) | CES2PDE2ARXRARXRBRXRG | |
| SCHEMBL7057873 | 0.79 | CES2 (0.42) | CES2PDE2ARXRARXRBRXRG | |
| SCHEMBL16488279 | 0.72 | CES2 (0.46) | CES2PDE2AKIF11LRRK2CYP3A4 | |
| SCHEMBL28770910 | 0.68 | PDE2A (0.50) | CES2PDE2AMETAP2 | |
| SCHEMBL6118430 | 0.67 | L3MBTL1 (0.44) | L3MBTL1RAB9ACYP3A4CYP2D6MAPT | |
| SCHEMBL178010 | 0.67 | CYP3A4 (0.50) | KIF11CFTRL3MBTL1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181563-B1 | CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME | SDS BIOTECH CORP (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-10104891-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | SDS BIOTECH K.K. (JP) | 2018-10-23 | — | — | US | disclosed |
| US-20180235225-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2018-08-23 | — | — | US | disclosed |
| US-9980487-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | SDS BIOTECH K.K. (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20170231226-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | SDS BIOTECH K.K. (JP) | 2017-08-17 | — | — | US | disclosed |
| EP-3181563-A1 | CONDENSED 11-MEMBER RING COMPOUND AND AGRICULTURE AND HORTICULTURAL FUNGICIDE COMPRISING SAME | SDS Biotech K. K. (JP) | 2017-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170231226-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | CYP51A1, CYP4Z1, ERG28 | CES2 1287/4885PDE2A 731/4885KIF11 677/4885 |
| US-10104891-B2 | Fused 11-membered compounds and agricultural/horticultural fungicides containing them | CYP51A1, CYP4Z1, ERG28 | CES2 1287/4885PDE2A 731/4885KIF11 677/4885 |
| US-20180235225-A1 | FUSED 11-MEMBERED COMPOUNDS AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING THEM | CYP51A1, CYP4Z1, ERG28 | CES2 1287/4885PDE2A 731/4885KIF11 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.