Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003232 | 0.83 | RAB9A (0.53) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19003263 | 0.82 | SMN1; SMN2 (0.41) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19003240 | 0.80 | MAPT (0.57) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19003245 | 0.76 | BCHE (0.58) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL3590876 | 0.75 | MMP1 (0.74) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3590874 | 0.75 | MMP1 (0.74) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL18985528 | 0.74 | NQO2 (0.56) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19003466 | 0.74 | NQO2 (0.56) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL19003241 | 0.74 | TGM2 (0.52) | RAB9AMEN1KMT2AMAPTNPC1 | |
| SCHEMBL19003251 | 0.74 | EGFR (0.68) | RAB9AMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | claimed |
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |