Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985280 | 0.86 | KMT2A (0.46) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL18985306 | 0.74 | CYP1A2 (0.50) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL14085811 | 0.71 | ALDH1A1 (0.67) | SMN1; SMN2LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL8171276 | 0.70 | MMP1 (0.47) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL3617946 | 0.70 | MMP1 (0.47) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL3617947 | 0.70 | MMP1 (0.47) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL19003261 | 0.67 | MMP1 (0.59) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL5186995 | 0.67 | MEN1 (0.68) | NPC1RAB9AMEN1KMT2AHPGD | |
| SCHEMBL13652998 | 0.66 | MT-CO2 (0.58) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19003305 | 0.66 | MMP1 (0.63) | SMN1; SMN2NPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | claimed |