SCHEMBL1898711

SCHEMBL1898711

Cc1nc(O)c2ncn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c2n1

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
TP53 P04637 1/20 0.62
CYP2C19 P33261 1/20 0.60
NT5E P21589 1/20 0.60
HIF1A Q16665 1/20 0.60
ADORA2A P29274 4/20 0.59
ADORA2B P29275 3/20 0.59
ADORA3 P0DMS8 2/20 0.59
ADORA1 P30542 2/20 0.59
HPGD P15428 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1898718 1.00 LMNA (0.62) LMNATP53CYP2C19NT5EHIF1A
SCHEMBL11311292 0.90 ADORA3 (0.60) LMNATP53CYP2C19NT5EHIF1A
SCHEMBL11311318 0.90 ADORA3 (0.60) LMNATP53CYP2C19NT5EHIF1A
Xanthosine SCHEMBL6676995 0.88 LMNA (0.65) LMNATP53CYP2C19NT5EHIF1A
Xanthosine SCHEMBL188120 0.88 LMNA (0.65) LMNATP53CYP2C19NT5EHIF1A
Xanthosine SCHEMBL11523732 0.88 LMNA (0.65) LMNATP53CYP2C19NT5EHIF1A
Xanthosine SCHEMBL8665102 0.88 LMNA (0.65) LMNATP53CYP2C19NT5EHIF1A
SCHEMBL16619900 0.87 ADORA3 (0.64) NT5EADORA2AADORA2BADORA3ADORA1
2-Methyladenosine SCHEMBL278664 0.87 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B
2-Methyladenosine SCHEMBL18159462 0.87 LMNA (0.75) LMNANT5EHIF1AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230407419-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2023-12-21 US disclosed
US-11732315-B2 Rapid diagnostic test for lamp NEW ENGLAND BIOLABS, INC. (US) 2023-08-22 US disclosed
CN-116529363-A RNA-guided clearance of herpes simplex virus type I and other related human herpesviruses 天普大学-联邦高等教育系统 2023-08-01 CN disclosed
US-20230048863-A1 Rapid Diagnostic Test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2023-02-16 US disclosed
US-20230022745-A1 Methods for Labeling a Population of RNA Molecules NEW ENGLAND BIOLABS, INC. (US) 2023-01-26 US disclosed
EP-4118233-A1 A RAPID DIAGNOSTIC TEST FOR LAMP New England Biolabs, Inc. (US) 2023-01-18 EP disclosed
EP-4110945-A2 A RAPID DIAGNOSTIC TEST FOR LAMP New England Biolabs, Inc. (US) 2023-01-04 EP disclosed
US-11525166-B2 Rapid diagnostic test for LAMP NEW ENGLAND BIOLABS, INC. (US) 2022-12-13 US disclosed
US-11479766-B2 Methods for labeling a population of RNA molecules NEW ENGLAND BIOLABS, INC. (US) 2022-10-25 US disclosed
CN-105518146-B Therapeutic uses of genome editing with CRISPR/Cas systems 哈佛学院校长同事会 2022-07-15 CN disclosed
WO-1997033590-A1 A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS NOVO NORDISK A/S (DK) 1997-09-18 WO disclosed
WO-1997033591-A1 A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS NOVO NORDISK A/S (DK) 1997-09-18 WO disclosed
US-5484774-A 2, N6 -disubstituted adenosines, tri-O-ester derivatives and their pharmaceutical compositions to treat ischemias NOVO NORDISK A/S (DK) 1996-01-16 US disclosed
EP-0675896-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1995-10-11 EP disclosed
US-5430027-A 2-chloro-N6 -substituted adenosines, their pharmaceutical compositions, and activity in treating ischemias NOVO NORDISK A/S (DK) 1995-07-04 US disclosed
EP-0607367-A1 NOVEL ADENOSINE DERIVATIVES NOVO NORDISK A/S (DK) 1994-07-27 EP disclosed
WO-1994014832-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1994-07-07 WO disclosed
EP-0603348-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1994-06-29 EP disclosed
WO-1993023417-A1 NOVEL ADENOSINE DERIVATIVES NOVO NORDISK A/S (DK) 1993-11-25 WO disclosed
WO-1993023418-A1 PURINE DERIVATIVES NOVO NORDISK A/S (DK) 1993-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11479766-B2 Methods for labeling a population of RNA molecules RNGTT, RNMT, MTAP LMNA 2087/4885TP53 1802/4885CYP2C19 4739/4885
US-20230022745-A1 Methods for Labeling a Population of RNA Molecules RNGTT, RNMT, MTAP LMNA 2087/4885TP53 1802/4885CYP2C19 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.