Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4848522 | 0.91 | CA2 (0.34) | CA2TAAR1LMNA | |
| SCHEMBL446130 | 0.91 | CYP1A2 (0.48) | TAAR1CYP1A2CYP2A6HRH3NPC1 | |
| SCHEMBL8718611 | 0.91 | LPL (0.43) | CA2GFERNPC1RAB9AKDM4E | |
| SCHEMBL523393 | 0.87 | TDP1 (0.48) | TAAR1LMNACYP1A2CYP2A6AOC3 | |
| SCHEMBL3195033 | 0.83 | LMNA (0.38) | CA2TAAR1LMNAESR1CYP1A2 | |
| SCHEMBL7975654 | 0.83 | ALDH1A1 (0.42) | CA2TDP1 | |
| SCHEMBL8319815 | 0.83 | CA2 (0.40) | CA2LMNACYP1A2NPC1TDP1 | |
| SCHEMBL10338732 | 0.80 | PPARA (0.42) | TAAR1KDM4E | |
| SCHEMBL8953816 | 0.77 | TAAR1 (0.45) | TAAR1LMNACYP1A2AOC3CYP2D6 | |
| SCHEMBL15952484 | 0.77 | ESR1 (0.40) | CA2TAAR1LMNAESR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674037-B2 | Silicon-containing polymer, method of manufacturing thereof, and curable polymer composition | DOW CORNING TORAY COMPANY, LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20110118413-A1 | SILICON-CONTAINING POLYMER, METHOD OF MANUFACTURING THEREOF, AND CURABLE POLYMER COMPOSITION | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-05-19 | — | — | US | disclosed |
| US-5726336-A | REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1998-03-10 | — | — | US | disclosed |